Abstractvolatile oils obtained by hyrodistillation hd and solvent free microwave extraction sfme from the aerial parts of ferula gummosa apiaceae were analyzed by means of gc and gcms. Ferula gummosa boiss flower and leaf extracts inhibit. Transcriptome and metabolome analysis of ferula gummosa boiss. Pdf composition and antimicrobial activity of the oils. Chemical composition of the essential oil from oleogumresin. Synergistic effects of ferula gummosa and radiotherapy on. Since time immemorial, the oleogumresins of ferula assafoetida and f. Apiaceae journal of medicinal plants and byproduct. The aim of this study was to investigate the effect of daily administration of f. Barije ferula gummosa eo was encapsulated into nanoliposomes. A total of twentyfour compounds were identified, which constitute 98% of the volatile oil. Ferula gummosa, a traditional medicine with novel applications. Click on column headings to sort table by that column. Abstractgalbanum is an aromatic oleogumresin forms as a pharmaceutical and industrial product of the species ferula gummosa boiss.
Marcellus empiricus, also known as marcellus burdigalensis marcellus of bordeaux, was a latin medical writer from gaul at the turn of the 4th and 5th centuries. Sesquiterpene coumarins from ferula gumosa journal of. All structured data from the file and property namespaces is available under the creative commons cc0 license. In this study, we examined the level of cellular oxidants, cytotoxicity, apoptosis and differentiation induced by oleo resin gum from ferula gummosa 30250 gml, as well as arsenic trioxide 50 m, as positive control, in leukemic nb4 and hl60 cells and normal polymorph nuclear. Ferula from latin ferula, rod is a genus of about 170 species of flowering plants in the family apiaceae, native to the mediterranean region east to central asia, mostly growing in arid climates.
Chemical composition of essential oils from aerial parts. This page was last edited on 11 octoberat the flowers are usually yellow, rarely white, produced in large umbels. Galbanum resin incense magic iran source ancient purity. Addition of cholesterol to the nanoliposomes lecithin bilayer increased the particle size. Before sharing sensitive information online, make sure youre on a. Mojtahedi, effects of ferula gummosa leaf oil of f. A total of forty two compounds were identified in the hyrodistilled oil accounting for 96. Ferula assafoetida l is one of these species that grows wildly in central area of iran. Seed dormancybreaking and germination requirements of ferula. Transcriptome and metabolome analysis of ferula gummosa.
Ferula gummosa ferula gummosa ferule gommeuse classification regne plantae division magnoliophyta classe magnoliopsida ordre apiales famille apiaceae genre ferula espece ferula gummosa boiss. Many other species of ferula genus also produce gums, but of greatly varying qualities. Endophytes were identified using morphological and then molecular characteristics. E, while seeds of ferula gummosa were collected in july 2005 from mazandaran province, around 36 26.
Antioxidant activity of flower, stem and leaf extracts of. After preparing the essential oilsof prangos frulacea, ziziphora tenuior, ferula gummosa,and. Chemical composition and antibacterial activity of the essential oils. These rats received nacl solution that was injected with 0. This experimental in vitro study has been performed in dental school of zanjanin 2014 15. Mining ferula gummosa transcriptome to identify mirnas. The morphophysiological dormancy of ferula ovina seeds is. In the present study, the oleogumresin and four organs root, flower, stem, and leaf of f. Effects of galbanum oil on patients with knee osteoarthritis. Variation in fruit morphological traits and bioacti ve ferula. Rate and percentage of seed germination decreased by drought stress. Materials and methods seeds of ferula ovina were collected in august 2005 from khorasan shomaly province, around 37 25. Among about 30 related species to the ferula genus, which are located in iran, ferula tabasensis, ferula persica, and f. Mar 01, 2018 ferula gummosa is known for the exudation of galbanum, an invaluable oleogumresin, that is composed of two important parts including terpenes and gums najafabadi et al.
Request pdf ferula gummosa, a traditional medicine with novel applications ferula gummosa with the persian name of barijeh is reputed due to its traditional history. Naturally pure, essential galbanum oil ferula gummosa. Chemical composition of essential oils from aerial parts of. Pdf composition and antimicrobial activity of the oils of. Metabolic profile, bioactivities, and variations in the. Both groups nonirradiated and irradiated were incubated for. Ferula gummosa is a monocarpic plant which is native to iran. The aim of this study was to determine the antioxidant and antihemolytic activities of the hydroalcoholic extract of ferula gummosa boiss flowers, stems. Kondo, t, miura, t, okubo, n, shimada, m, baskin, c and baskin, j 2004 ecophysiology of deep simple epicotyl morphophysiological dormancy in seeds of gagea. Search contacts top 10 contacts key points in writing articles advanced search. Ferula foetida, ferula narthex, ferula narthex, and ferula scorodosoma all yield the resin commercially. Ferula gummosa boiss apiaceae is an extremely precious medicinal plant which naturally grows throughout the mediterranean and central asia.
Ecological and phytochemical attributes of endemic ferula. Mar 01, 2012 the monoterpenic composition of the essential oil of oleogumresin ferula gummosa boiss from iran was studied by gc. The dried flowers and leaves were ground in a blender and ca. Antioxidant and antitumor effects of ferula sinkiangensis k. Effect of ferula gummosa ethanolic extract on osteogenesis in. Galbanum is an aromatic gum resin and a product of certain umbelliferous persian plant species in the genus ferula, chiefly ferula gummosa synonym f. Chemical composition of the essential oil from oleogum. Extraction of chemical composition of volatile oil of. According to our knowledge there is no scientific report on the antioxidant activity of ferula gummosa leaves, flowers or stems.
Traditional gum gathering is done with a locally made, wroughtiron tool. The plant gives flowers, fruits, and seeds at the last year of life normally 7 years old. Article information, pdf download for evaluation of antiinflammatory. Ferula pseudalliacea bitter asafetida is an endemic medicinal plant grown in the center of iran. Ferula gummosa galbanum has been used in traditional medicine since ancient time. Ferula species known for its oleoresins that are recognized valuable industrial crops and food products. Nanoliposomes with eo had antimicrobial activity against e. The volatile oils from the oleogumresins of ferula assafoetida and. Variation in fruit morphological traits and bioacti ve. Experiments included temperature requirements for both embryo growth and germination under field and laboratory conditions, the effects of warm stratification, gibberellic acid ga 3, dry afterripening, exogenous. Drought was imposed by applying 0%, 5%, 10% and 15% concentrations of polyethylene glycol peg 6000. Galbanum is an aromatic gum resin, the product of an umbelliferous iranian persian plant species, ferula gummosa or galbaniflua. Ferula gummosa is known for the exudation of galbanum, an invaluable oleogumresin, that is composed of two important parts including terpenes and gums najafabadi et al. The antimicrobial activity of the oil was tested on three strains of gram positive bacteria staphylococcus aureus, s.
Type a value in the celsius field to convert the value to fahrenheit. Evaluation of antiinflammatory and some possible mechanisms of. Metabolic differences of two ferula species as potential. The chemical composition of the ferula gummosa extracted by carbon nanotube profile is presented in table 2 chromatogram 2. Until recently, the essential oil composition from different parts of the plant in comparison with the oleogumresin remains mostly unclear. In this study, the antioxidant and antitumor effects of the extract frastions of ferula sinkiangensis k. Antimicrobial and cytotoxic activity of ferula gummosa plant. This study was conducted to better understand the dormancy and germination behaviour of its seeds. Dukes phytochemical and ethnobotanical databases at nal.
To best of our knowledge there is no scientific report on antioxidant activity of f. Effect of drought stress on germination and antioxidants. These include noradrenergic system smooth muscle relaxant activity aqel et al. However, we believe that these studies have not shown a complete picture of dormancy in f. The oleogum resin of ferula has been used in paint, varnish, soap, detergent, food, and perfume industries 14. Deeper insight into the monoterpenic composition of ferula. Effect of essential oils from callistemon viminalis and. May 26, 2020 ferula gummosa, a traditional medicine with novel applications.
Ferula gummosa boiss is a good source of biologically active compounds such as monoterpene and sesquiterpene derivatives. Feb 01, 2021 phylogenetic position of the genus ferula apiaceae and its placement in tribe scandiceae as inferred from nrdna its sequence variation. Antioxidant activity of hydroalcholic extract of ferula. The rats in this group performed an aerobic training protocol similar to that in group 3, and in addition, received lname and ferula gummosa supplement. Gcms and hptlcbased methods of comparison among standard. Study of antioxidant activity of bacterial endophyte extracts. Ferula gummosa in the germplasm resources information network grin, u. Department of agriculture agricultural research service. In this study, effects of aqueous, methanolic and acetone extracts of the seed and root of this plant in experimental models of acute pain tailflicktf, chronic pain formalin testft and inflammation cotton pellet granulomacpg was investigated. Comparative morphology and fruit anatomy of ferula.
Ferula gummosa boiss apiaceae has been used in iranian traditional medicine for the relief of stomach pain. The leaves are tripinnate or even more finely divided, with a stout basal sheath clasping. Antimicrobial and cytotoxic activity of ferula gummosa. Medicinal plants used in iranian traditional medicine to treat. Ferula were conducted using one species originating from a limited geographical area nabavi et al. Nov 15, 2015 moreover, the alcohol extract of the ferula gummosa root has been shown to reduce the hemolysis induced by hydrogen peroxide in rats, with similar effects as vitamin c 1012. Antifungal activity of essential oils of prangos frulacea. Ferula gummosa boiss were collected from damavand mountains in northern iran. It was used in classical romeit may be that our worcestershire sauce is a descendent of those ancient asafoeditalaced concoctions. Galbanum is an aromatic oleogumresin forms as a pharmaceutical and industrial product of the species ferula gummosa boiss. They may forget how to brush their teeth or comb their hair.
The usage of medicinal plants as natural antimicrobial agents has grown in many fields including dental medicine. Antioxidant and antitumor effects of ferula sinkiangensis. Materials and methods in this study, 20 bacterial isolates were isolated from different organs of the plant. There are also several reports on antioxidant effects of these compounds. This study highlighted the strong antibacterial effect of ferula. This study allowed to tentatively identify monoterpenic compounds including 24 hydrocarbons, 52 alcohols, 4 ethers, 20 aldehydes, 8 oxides, 18 ketones, 1 furan and 3 epoxides, from which only 25 were reported before in this species. They are herbaceous perennial plants growing to 14 m tall, with stout, hollow, somewhat succulent stems. Terpenes are the most important part of the olegumresin for both industrial and pharmaceutical purposes paduch et al. Pdf protective effect of ferula gummosa hydroalcoholic. In the treatment of 15% was not observed seed germination. After harvesting, flowers and leaves were dried in dark, at room temperature for 7 days.
A new sesquiterpene coumarin, gumosin 1, two new sesquiterpene coumarin glycosides, gumosides a 2 and b 3, and 10 known compounds, namely, cauferoside 4, feselol 5, conferoside, ferilin, ferocaulidin, ligupersin a, conferol, and daucosterol, and the phenolic compounds acantrifoside e and 4hydroxybenzoic acid 46osulfoglucopyranoside, were isolated from a methanolic extract of. The antihypoxic and antioxidant activities of ferula gummosa roots were investigated. Ferula gummosa galbanum pfaf plant database plants for a future. The antinociceptive and antiinflammatory effects of ferula gummosa was investigated by mandegary et al. Therefore, the essential oil from galbanum, root, stem, flower. The authors alone are responsible for the content and writing of this article. Galbanum is traditionally used for treating different diseases including flatulence and memory impairment.
Ferula gummosa gum induces apoptosis via ros mechanism in. Pdf individual and concomitant effects of cardioprotective. Original article open access chemical composition and. Ferula gummosa galbanum oil knee osteoarthritis pain morning stiffness. Effects of ferula macrecolea essential oil against echinococcus granulosus protoscoleces. Despite the fabulous value of galbanum, very little information on the genetic and biochemical mechanisms of its production existed. The story of the tabernacle incense is in exodus 30. Usda, ars, germplasm resources information network. Ferula ovina is a perennial apiaceae with great medicinal and economic value.
It is in flower from may to june, and the seeds ripen from june to august. Media in category ferula gummosa the following 3 files are in this category, out of 3 total. A total of 34 compounds were identified, which constitute 98% of the volatile oil. Effect of ferula gummosa extract on renal tbars levels a and sod activity b during chronic lname administration in rats. Keshtkar, hr, azarnivand, h, etemad, v and moosavi, ss 2008 seed dormancy breaking and germination requirements of ferula ovina and ferula gummosa. Effect of longterm administration of ferula gummosa root. The highest antimicrobial activity was observed in pure lecithin nanoliposomes. Extraction of chemical composition of volatile oil of ferula. Issn 23203862 comparative study of volatile oils extracted. Chemical composition of essential oils from aerial parts of ferula gummosa apiaceae in jajarm region, iran using traditional hydrodistillation and solventfree microwave extraction methods.
1072 737 1594 1212 1553 1259 967 1479 595 67 676 224 4 330 173 198 1453 1345 1058 927 1164 1290 1615 222 318 65 401 107 660